The actress appeared on Bravo’s “Watch What Happens Live” with Andy Cohen on Sunday night and appeared to call the rapper’s sexuality into question.

Fox, who has a new role on the hit Fox series “Empire,” was on “WWHL” along with “Real Housewives of Atlanta” cast member Kandi Burruss when Cohen asked Fox about a comment the rapper reportedly made about her show.

“What were your thoughts when 50 Cent blamed the season ratings dip on ‘gay stuff’?” Cohen asked.

“First of all, you know the pot called the kettle black is all I’m saying,” Fox replied.

A visibly stunned Cohen fanned himself as Burruss also expressed shock.

Fox, who dated the rapper in 2003, paused for a bit before answering “no, he’s not” when Cohen asked whether 50 Cent was gay. She added, “He just seems like he’s got something that’s not quite clear.” She also mentioned a magazine cover featuring him and fellow artist Soulja Boy that she said gave her pause

The comments immediately set Twitter afire, with people speculating that 50 Cent would not respond well.

50 Cent did indeed respond with a few profane Instagrams in which he called out Fox for being jealous of fellow actress Halle Berry, claiming Fox told him that she “could have played all the roles (Berry) did better then her.”

Soulja Boy also slapped back on Instagram, posting a not very flattering photo of Fox with the caption, “Everybody hit up this cougar..she’s single & ready to mingle …1-800-GrannyDesperateForAttention extension I’mWashedUp.”

Fox responded to some of the tweets, including those implying that the rapper might try to take revenge by spilling secrets about her. Apparently, she’s not worried, as she tweeted, “I got some stories I stored in my vault too!”

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